What Is Topamax (Topiramate)?
Topamax is the brand name of topiramate, an anticonvulsant medicine used to stop seizures and decrease the regularity of migraines.
When it is precise mechanism of action is unspecified , scientific studies recommend Topamax may alter the production or action of neurotransmitters in the brain , reducing the irregular activity of the nerves in the brain that cause seizures or stopping the abnormal activity from spreading to different nerves . Various other researchers have recommended that it may decrease the nerves instantly, thus which makes them unlikely to fire.
The Food and Drug Administration (FDA) approved Topamax to treat seizures in 1996.
In 2004, Topamax got FDA authorization for the prevention of migraines. Made by Janssen Pharmaceuticals, Topamax has become the number-one pharmaceutical drugs for migraine prevention in the USA.
It is used to stop migraine headaches from arising in those 12 and older. It cannot be used to treat a headache which has already started, however it might help to decrease the lots of painful migraine.
Topamax and Weight Loss
Doctors sometimes recommend Topamax off-label to control binging and purging and encourage weight loss in individuals with eating disorders for example bulimia nervosa and binge-eating disorder.
Topamax (Topiramate) Side Effects
Typical Side Effects of Topamax (Topiramate)
Certain side effects of Topamax might go away after your body becomes used to the drugs. When they do not disappear or become worse, let your family doctor know. The typical issues within this category are tremors and breast pain in women.
A few of the less typical side effects can include leg, chest, and back pain along with constipation, heartburn, increased sweating, and hot flushes.
Side effects that require that you talk to your doctor immediately:
Blurred or rapidly reducing vision
Eye pain and redness
Increased eye pressure
Burning, prickling or tingling sensations
Other symptoms that need attention:
Continuous, uncontrolled back-and-forth or rolling eye movements
Menstrual pain and changes
Slowing of mental and physical activity
Unusual weakness or always wanting to sleep
Severe Side Effects of Topamax (Topiramate)
Mood alterations for example aggression, agitation, apathy, and depression symptoms
Loss of appetite
Fever, chills or sore throat
Reduced sensation or perception
Red, irritated, or bleeding gums
Uncommon side effects:
Blood in urine
Frequent, difficult or uncomfortable urination
Loss of bladder control
A decrease in sexual desire
Ringing or buzzing in the ears
Red or sore eyes
Lower back or side pain
Topamax (Topiramate) Dosage
Topamax comes in tablets ( 25 milligrams ( mg ) , 50 mg , 100 mg , and 200 mg ) , prolonged release oral capsules ( 25 mg , 50 mg , 100 mg , 150 mg , 200 mg ) , and sprinkle capsule ( 15 mg and 25 mg ) that may be taken orally or sprinkled onto soft meals .
People who take Topamax commonly begin with a reduced dose of 25 or 50 mg daily (divided over 2 doses), increasing it gradually by 25 to 50 mg each week until an effective every day dose is reached.